Validation of Computerized Systems – Guide to Preparing the Systems Inventory

In the pharmaceutical industry, computerized systems impacting GxP environments must adhere to strict regulations to ensure product quality and patient safety. A documented inventory is essential for controlling these systems, identifying their GxP impact, and assessing their associated risk levels. This inventory supports regulatory compliance, facilitates audits, and enables strategic planning of systems, contributing to transparency and data integrity.

Safe Transportation of Psychotropics in the Pharmaceutical Industry

The transportation of psychotropics within the pharmaceutical industry is a complex and highly regulated process due to their potential for abuse and impact on health. These medications require specialized handling and compliance with international and local regulations, including permits and comprehensive tracking of product movement. Key challenges include regulatory compliance, storage conditions, security and traceability, and proper documentation. Best practices encompass real-time monitoring, staff training, security protocols, and risk management. Technology, such as IoT and blockchain, has enhanced transparency in the supply chain, ensuring the efficient distribution of these critical medications.

The Critical Role of the Microbiome in Neurodegenerative Diseases: Perspectives and Challenges

Discover the critical role of the microbiome in neurodegenerative diseases and the challenges facing current research. This blog explores the significance of the gut-brain connection, the bidirectional operation of the Central Nervous System-Gut-Microbiota axis, and the implications for conditions like Parkinson’s and Alzheimer’s. Despite emerging concerns about research validity, there is substantial evidence supporting the microbiome’s involvement in neurological health. Learn about the complexities and future directions for microbiome studies, emphasizing the need for rigorous clinical trials to unlock new therapeutic strategies.

Management Control in a Laboratory: Optimization and Strategic Oversight

Management Control in a Laboratory: Optimization and Strategic Oversight” discusses the vital role of management control in overseeing pharmaceutical activities. It covers budgeting, performance monitoring, and strategic decision-making to ensure efficiency and goal achievement in a medical laboratory setting.

Challenges in Developing Adhesive Layers for Medicinal Patches

Ensuring adhesion throughout the use of a medicinal patch is crucial for providing safe and reliable products. Discover how an adhesive overlay can be the solution to adhesion problems and the challenges its formulation presents. From compatibility with the active ingredient to the ideal size and the ability to avoid interfering with drug release, delve into the complex technical aspects that make medicinal patches effective.

Ethical Alternatives in Research

Advances in ethical alternatives to animal experimentation, such as in vitro models and the implementation of the “3R” principle, show a growing commitment to animal welfare, improving research quality, and protecting the environment. These practices offer more relevant results for humans while addressing ethical and scientific concerns. Integrating humane and effective methods like cell models, toxicogenomics, and computational models promotes more ethical, accurate, and sustainable research.

Evolution of the transdermal market: mergers, diversification, and business opportunities

Transdermal patches, those discreet allies we adhere to our skin to release drugs in a controlled manner, have come a long way since their introduction in 1979. While they have multiple advantages, they have not reached the market massively due to the significant challenges that a molecule must overcome to be administered by this route. To highlight this minority participation within the array of means to administer drugs to the body, we can mention that between 2015 and 2022, only 84 transdermal patches were approved out of a total of 7239 generic products by the FDA, representing just 1.2% of these products. 

The Future of Scientific Publishing

Scientific publishing faces evolution: from prestigious journals to commercial giants. Concerns arise over access barriers, rising costs, and the emergence of predatory publishers. The future hinges on open access and digitalization, shaping a dynamic landscape for knowledge exchange.

Sustainable Future in the Pharmaceutical Sector

Environmental sustainability is a fundamental pillar for maintaining a harmonious balance between humans and their natural environment. This implies creating programs that promote awareness of the environmental impact of our daily actions, as well as the products and services we consume.

Uniting forces for a healthy future

In the current crossroads of planetary challenges, the interrelation between the climate crisis and biodiversity loss serves as a wake-up call for humanity. These two seemingly distinct phenomena are intrinsically intertwined, and the failure to address them collectively poses significant risks to the sustainability of life on Earth.