Amarin Technologies S.A. offers a patent-protected technology for transdermal and topical delivery systems (patches) and semi-solid topical and systemic formulations (gels and creams).
Amarin´s patches are of type:
- Monolayer drug-in-adhesive.
- Bilayer drug-in-adhesive.
- Matrix system for delivery of liquid drugs.
The devices (patches) designed and manufactured by our Company consist of thin units, which contain the active principles in a matrix composed of pressure-sensitive adhesives and excipients such as permeation enhancers, co-solvents and antioxidants.
Transdermal delivery systems (TDS) provide therapy for periods between one and seven days. The increase in the interval between applications favors patient compliance and, in certain cases, optimizes caregivers work.
Another advantage of transdermal administration of drugs is the possibility of reaching sustained and controllable levels of drug in plasma, avoiding peaks and troughs characteristics of the oral or injectable routes of administration, thus decreasing the risk of potential side effects or lack of activity.
The Company has also developed an “enhancer” technology applied on gels. The drug permeation using this technology allows to reach therapeutic levels of drugs in the target structures.