Kimberley Pardo – Marketing and Business Development Analyst
The skin is a natural barrier that protects our body, but it is also permeable to various substances, including some medications. Low molecular weight and high liposolubility molecules are ideal for transdermal administration, as they are easily absorbed through the skin. Medicinal patches are pharmaceutical preparations designed to modify skin permeation for a specific group of drugs, ensuring a constant permeation and optimal drug delivery. This administration method is particularly useful in long-term treatments, as it ensures a constant and sustained release of active ingredients. Additionally, since the drugs are absorbed through the skin, they bypass the gastrointestinal system, reducing the risk of adverse reactions. This is one of the significant advantages of transdermal patches.
Advantages of Patches: As mentioned in the following article, the benefits of using transdermal patches over other administration methods include:
• Better bioavailability • Controlled and consistent administration • Non-invasive • Easy application • Improved patient compliance
To ensure the proper handling of transdermal patches, it is important to follow these recommendations on how to use them:
• Skin Preparation: Before applying the patch, make sure the skin is clean and dry. Avoid applying it over makeup, creams, lotions, or other topical products that may interfere with adhesion.
• Choice of Area: Choose areas with little hair, such as the outer arm or upper torso, where there is no friction with clothing.
• Avoid Certain Areas: Do not apply the patch on areas with scars, burns, or irritation, or over bones like elbows or knees, to ensure good drug absorption.
• Hand Washing: Wash your hands well before and after handling the patch. Remove the patch from its protective packaging and apply it to the skin, pressing gently for about 10 seconds to ensure adhesion.
• Do Not Modify Patches: Do not cut, fold, or split patches, as this can alter the drug release, causing overdose or reducing effectiveness. If you need a lower dose, use a lower dose patch as prescribed.
• Rotation of Areas: Alternate the application area to avoid local allergic reactions.
• Proper Disposal: Dispose of used, expired, or unused patches properly. Fold the patches so the adhesive side sticks to itself for safe disposal.
• Keep Out of Reach of Children: Like any medication, patches should be kept out of reach of children to prevent accidental ingestion.
In summary, transdermal patches represent a valuable tool in the therapeutic arsenal, offering significant benefits and facilitating medication administration for many patients.
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