In the 17th century, scientific work was disseminated through prestigious entities like academies or universities. Manuscripts were reviewed and published based on the institution members' judgment. This method persisted until the 20th century when commercial publishers led to the emergence of Peer Review and the Journal Impact Factor (JIF). Open Access, which advocates for free access to scientific information, also became important. Despite facilitating scientific communication, these factors also led to problems like plagiarism and data fabrication.
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Scientific publishing faces evolution: from prestigious journals to commercial giants. Concerns arise over access barriers, rising costs, and the emergence of predatory publishers. The future hinges on open access and digitalization, shaping a dynamic landscape for knowledge exchange.
Environmental sustainability is a fundamental pillar for maintaining a harmonious balance between humans and their natural environment. This implies creating programs that promote awareness of the environmental impact of our daily actions, as well as the products and services we consume.
Work-related accidents pose a constant concern in the industry, where the safety and well-being of employees are paramount. In this article, we will explore the crucial measures that must be implemented to prevent accidents, the responsibilities of companies, and the tools available to ensure a safe work environment.
In the current crossroads of planetary challenges, the interrelation between the climate crisis and biodiversity loss serves as a wake-up call for humanity. These two seemingly distinct phenomena are intrinsically intertwined, and the failure to address them collectively poses significant risks to the sustainability of life on Earth.
The growing prevalence of Alzheimer's-type dementia, with over 35 million current cases and a projection to exceed 135 million by 2050, underscores the urgency of understanding and addressing challenges associated with neurodegenerative diseases.
Many companies, once focused solely on developing transdermal patches, are now also venturing into transmucosal forms, such as oral films.
According to the World Health Organization, the abusive consumption of certain drugs and substances has increased in recent years, resulting in serious consequences for the population, including neurological damage, motor disabilities, addiction, overdoses, and even death. While traditional pharmaceutical forms such as tablets are frequently abused, transdermal patches, especially those containing opioids, should also be considered.
Transdermal patches present certain attributes that make the efficacy, safety, and quality of the product and must be controlled in the laboratory through analytical techniques to ensure the performance and safety of the transdermal delivery system (or TDS). Some of them correspond to tests that are common to other pharmaceutical forms. However, due to the particular characteristics of transdermal patches, there are specific procedures that apply to TDSs and that are described in internationally recognized regulations and pharmacopoeias.
In the pharmaceutical business, supply chain management plays a fundamental role in delivering the necessary raw materials for the production of safe pharmaceutical forms intended for patients and end consumers. It also involves the precise and timely coordination of finished products not only for the domestic market but also for the export market.
The use of Quality by Design (QbD) concept to medicated plasters (patches) development gives us the certainty to obtain safety and reliable products for patients with verifiable efficacy, long before they enter their production stage.
Patient advocacy groups play a crucial role in drug development. They work to ensure that patients have access to safe, effective, and affordable drugs.
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