Ethical Alternatives in Research

Advances in ethical alternatives to animal experimentation, such as in vitro models and the implementation of the “3R” principle, show a growing commitment to animal welfare, improving research quality, and protecting the environment. These practices offer more relevant results for humans while addressing ethical and scientific concerns. Integrating humane and effective methods like cell models, toxicogenomics, and computational models promotes more ethical, accurate, and sustainable research.

Evolution of the transdermal market: mergers, diversification, and business opportunities

Transdermal patches, those discreet allies we adhere to our skin to release drugs in a controlled manner, have come a long way since their introduction in 1979. While they have multiple advantages, they have not reached the market massively due to the significant challenges that a molecule must overcome to be administered by this route. To highlight this minority participation within the array of means to administer drugs to the body, we can mention that between 2015 and 2022, only 84 transdermal patches were approved out of a total of 7239 generic products by the FDA, representing just 1.2% of these products. 

Fake Papers

In the 17th century, scientific work was disseminated through prestigious entities like academies or universities. Manuscripts were reviewed and published based on the institution members’ judgment. This method persisted until the 20th century when commercial publishers led to the emergence of Peer Review and the Journal Impact Factor (JIF). Open Access, which advocates for free access to scientific information, also became important. Despite facilitating scientific communication, these factors also led to problems like plagiarism and data fabrication.

The Future of Scientific Publishing

Scientific publishing faces evolution: from prestigious journals to commercial giants. Concerns arise over access barriers, rising costs, and the emergence of predatory publishers. The future hinges on open access and digitalization, shaping a dynamic landscape for knowledge exchange.

Work-related accidents in the industry

Work-related accidents pose a constant concern in the industry, where the safety and well-being of employees are paramount. In this article, we will explore the crucial measures that must be implemented to prevent accidents, the responsibilities of companies, and the tools available to ensure a safe work environment.

Strategies to Deter Abuse in Transdermal Patches

Strategies to Deter Abuse in Transdermal Patches

According to the World Health Organization, the abusive consumption of certain drugs and substances has increased in recent years, resulting in serious consequences for the population, including neurological damage, motor disabilities, addiction, overdoses, and even death. While traditional pharmaceutical forms such as tablets are frequently abused, transdermal patches, especially those containing opioids, should also be considered.

How do we control the quality of transdermal patches?

Transdermal patches present certain attributes that make the efficacy, safety, and quality of the product and must be controlled in the laboratory through analytical techniques to ensure the performance and safety of the transdermal delivery system (or TDS). Some of them correspond to tests that are common to other pharmaceutical forms. However, due to the particular characteristics of transdermal patches, there are specific procedures that apply to TDSs and that are described in internationally recognized regulations and pharmacopoeias.

The Importance of Supply Chain Management in the Pharmaceutical Industry

In the pharmaceutical business, supply chain management plays a fundamental role in delivering the necessary raw materials for the production of safe pharmaceutical forms intended for patients and end consumers. It also involves the precise and timely coordination of finished products not only for the domestic market but also for the export market.