Strategies to Deter Abuse in Transdermal Patches

Strategies to Deter Abuse in Transdermal Patches

According to the World Health Organization, the abusive consumption of certain drugs and substances has increased in recent years, resulting in serious consequences for the population, including neurological damage, motor disabilities, addiction, overdoses, and even death. While traditional pharmaceutical forms such as tablets are frequently abused, transdermal patches, especially those containing opioids, should also be considered.

How do we control the quality of transdermal patches?

Transdermal patches present certain attributes that make the efficacy, safety, and quality of the product and must be controlled in the laboratory through analytical techniques to ensure the performance and safety of the transdermal delivery system (or TDS). Some of them correspond to tests that are common to other pharmaceutical forms. However, due to the particular characteristics of transdermal patches, there are specific procedures that apply to TDSs and that are described in internationally recognized regulations and pharmacopoeias.

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