The transportation of psychotropics within the pharmaceutical industry is a complex and highly regulated process due to their potential for abuse and impact on health. These medications require specialized handling and compliance with international and local regulations, including permits and comprehensive tracking of product movement. Key challenges include regulatory compliance, storage conditions, security and traceability, and proper documentation. Best practices encompass real-time monitoring, staff training, security protocols, and risk management. Technology, such as IoT and blockchain, has enhanced transparency in the supply chain, ensuring the efficient distribution of these critical medications.